7XU5
Structure of SARS-CoV-2 D614G Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Closed Conformation
Summary for 7XU5
Entry DOI | 10.2210/pdb7xu5/pdb |
EMDB information | 33453 33459 |
Descriptor | Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... (4 entities in total) |
Functional Keywords | protein engineering, spike protein, sars-cov-2, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 3 |
Total formula weight | 384938.22 |
Authors | Qu, K.,Chen, Q.,Ciazynska, K.A.,Liu, B.,Zhang, X.,Wang, J.,He, Y.,Guan, J.,He, J.,Liu, T.,Zhang, X.,Carter, A.P.,Xiong, X.,Briggs, J.A.G. (deposition date: 2022-05-18, release date: 2022-07-20, Last modification date: 2022-08-17) |
Primary citation | Qu, K.,Chen, Q.,Ciazynska, K.A.,Liu, B.,Zhang, X.,Wang, J.,He, Y.,Guan, J.,He, J.,Liu, T.,Zhang, X.,Carter, A.P.,Xiong, X.,Briggs, J.A.G. Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. Plos Pathog., 18:e1010583-e1010583, 2022 Cited by PubMed: 35905112DOI: 10.1371/journal.ppat.1010583 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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