7XT0

Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors

Summary for 7XT0

Entry DOI	10.2210/pdb7xt0/pdb
Descriptor	RNA helicase, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	st. louis encephalitis virus, ns3 helicase, crystal structural, virtual screening, inhibitors, hydrolase
Biological source	Saint Louis encephalitis virus
Total number of polymer chains	1
Total formula weight	50278.01
Authors	Wang, D.P.,Jiang, F.Y.,Zeng, X.Y.,Zhao, R.,Chen, C.,Zhu, Y.,Cao, J.M. (deposition date: 2022-05-15, release date: 2023-11-01, Last modification date: 2025-05-14)
Primary citation	Wang, D.P.,Jiang, F.Y.,Zeng, X.Y.,Liu, Y.J.,Zhao, R.,Wang, M.Y.,Luo, J.,Chen, C.,Zhu, Y.,Cao, J.M. Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors. Genes Dis, 10:389-392, 2023 Cited by PubMed: 37223502 DOI: 10.1016/j.gendis.2022.07.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.48 Å)

Structure validation