7XST

Cryo-EM structure of SARS-CoV-2 Omicron spike glycoprotein in complex with three F61 Fab and three D2 Fab

7XST の概要

• エントリーDOI: 10.2210/pdb7xst/pdb
• EMDBエントリー: 33434
• 分子名称: Spike glycoprotein, F61 heavy chain, F61 light chain, ... (6 entities in total)
• 機能のキーワード: sars-cov-2, omicron spike, antibody, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 15
• 化学式量合計: 558768.83

構造登録者

Wang, X.,Li, X. (登録日: 2022-05-15, 公開日: 2022-11-23)

• 主引用文献: Li, X.,Pan, Y.,Yin, Q.,Wang, Z.,Shan, S.,Zhang, L.,Yu, J.,Qu, Y.,Sun, L.,Gui, F.,Lu, J.,Jing, Z.,Wu, W.,Huang, T.,Shi, X.,Li, J.,Li, X.,Li, D.,Wang, S.,Yang, M.,Zhang, L.,Duan, K.,Liang, M.,Yang, X.,Wang, X.; Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.; Cell Discov, 8:87-87, 2022; PubMed: 36075908; DOI: 10.1038/s41421-022-00449-4

実験手法

ELECTRON MICROSCOPY (3.04 Å)