7XRQ
The Catalytic Core Structure of Cystathionine beta-Synthase from Candida albicans
Summary for 7XRQ
Entry DOI | 10.2210/pdb7xrq/pdb |
Descriptor | Cystathionine beta-synthase, PHOSPHATE ION (3 entities in total) |
Functional Keywords | cystathionine beta-synthase, catalytic core center, lyase |
Biological source | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
Total number of polymer chains | 2 |
Total formula weight | 76629.60 |
Authors | Lou, H.X.,Yu, H.N.,Chang, W.Q. (deposition date: 2022-05-11, release date: 2023-04-19, Last modification date: 2023-11-29) |
Primary citation | Chang, W.,Zhang, M.,Jin, X.,Zhang, H.,Zheng, H.,Zheng, S.,Qiao, Y.,Yu, H.,Sun, B.,Hou, X.,Lou, H. Inhibition of fungal pathogenicity by targeting the H 2 S-synthesizing enzyme cystathionine beta-synthase. Sci Adv, 8:eadd5366-eadd5366, 2022 Cited by PubMed: 36525499DOI: 10.1126/sciadv.add5366 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.501 Å) |
Structure validation
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