7XNV

Structurally hetero-junctional human Cx36/GJD2 gap junction channel in soybean lipids (C6 symmetry)

Summary for 7XNV

• Entry DOI: 10.2210/pdb7xnv/pdb
• EMDB information: 33315 33327
• Descriptor: Gap junction delta-2 protein, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE (2 entities in total)
• Functional Keywords: connexin 36, cx36, gap junction channel, gjd2, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 12
• Total formula weight: 526242.01

Authors

Lee, S.N.,Cho, H.J.,Jeong, H.,Ryu, B.,Lee, H.J.,Lee, H.H.,Woo, J.S. (deposition date: 2022-04-29, release date: 2023-03-22)

• Primary citation: Lee, S.N.,Cho, H.J.,Jeong, H.,Ryu, B.,Lee, H.J.,Kim, M.,Yoo, J.,Woo, J.S.,Lee, H.H.; Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.; Nat Commun, 14:1347-1347, 2023; PubMed: 36906653; DOI: 10.1038/s41467-023-37040-8

Experimental method

ELECTRON MICROSCOPY (3.4 Å)