7XN9

Crystal structure of SSTR2 and L-054,522 complex

7XN9 の概要

• エントリーDOI: 10.2210/pdb7xn9/pdb
• 分子名称: Somatostatin receptor type 2,Endo-1,4-beta-xylanase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, tert-butyl (2S)-6-azanyl-2-[[(2R,3S)-3-(1H-indol-3-yl)-2-[[4-(2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]carbonylamino]butanoyl]amino]hexanoate (3 entities in total)
• 機能のキーワード: g protein-coupled receptor, somatostatin receptor 2, structural protein, signaling protein, signaring protein-inhibitor complex, signaring protein/inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 66942.22

構造登録者

Zhao, W.,Han, S.,Qiu, N.,Feng, W.,Lu, M.,Yang, D.,Wang, M.-W.,Wu, B.,Zhao, Q. (登録日: 2022-04-28, 公開日: 2022-08-03, 最終更新日: 2023-11-29)

• 主引用文献: Zhao, W.,Han, S.,Qiu, N.,Feng, W.,Lu, M.,Zhang, W.,Wang, M.,Zhou, Q.,Chen, S.,Xu, W.,Du, J.,Chu, X.,Yi, C.,Dai, A.,Hu, L.,Shen, M.Y.,Sun, Y.,Zhang, Q.,Ma, Y.,Zhong, W.,Yang, D.,Wang, M.W.,Wu, B.,Zhao, Q.; Structural insights into ligand recognition and selectivity of somatostatin receptors.; Cell Res., 32:761-772, 2022; PubMed: 35739238; DOI: 10.1038/s41422-022-00679-x

実験手法

X-RAY DIFFRACTION (2.6 Å)