7XL5

Crystal structure of the H42T/A85G/I86A mutant of a nadp-dependent alcohol dehydrogenase

Summary for 7XL5

• Entry DOI: 10.2210/pdb7xl5/pdb
• Descriptor: NADP-dependent isopropanol dehydrogenase (2 entities in total)
• Functional Keywords: dehydrogenase, oxidoreductase, mutant, thermoanaerobacter brockii
• Biological source: Thermoanaerobacter brockii
• Total number of polymer chains: 4
• Total formula weight: 153722.41

Authors

Jiang, Y.Y.,Qu, G.,Li, X.,Sun, Z.T.,Han, X.,Liu, W.D. (deposition date: 2022-04-21, release date: 2023-05-31, Last modification date: 2024-06-12)

• Primary citation: Jiang, Y.,Li, X.,Liu, B.,Tong, F.,Qu, G.,Sun, Z.; Engineering the hydrogen transfer pathway of an alcohol dehydrogenase to increase activity by rational enzyme design; Mol Catal, 530:112603-, 2022; DOI: 10.1016/j.mcat.2022.112603

Experimental method

X-RAY DIFFRACTION (2.604 Å)