7XJ3

Structure of human TRPV3

Summary for 7XJ3

• Entry DOI: 10.2210/pdb7xj3/pdb
• EMDB information: 33218
• Descriptor: fusion of transient receptor potential cation channel subfamily V member 3 and 3C-GFP, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate (2 entities in total)
• Functional Keywords: channel, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 493393.44

Authors

Fan, J.,Yue, Z.,Jiang, D.,Lei, X. (deposition date: 2022-04-14, release date: 2022-11-09, Last modification date: 2024-07-03)

• Primary citation: Fan, J.,Hu, L.,Yue, Z.,Liao, D.,Guo, F.,Ke, H.,Jiang, D.,Yang, Y.,Lei, X.; Structural basis of TRPV3 inhibition by an antagonist.; Nat.Chem.Biol., 19:81-90, 2023; PubMed: 36302896; DOI: 10.1038/s41589-022-01166-5

Experimental method

ELECTRON MICROSCOPY (3.54 Å)