7XHE
Crystal structure of CBP bromodomain liganded with CCS151
Summary for 7XHE
Entry DOI | 10.2210/pdb7xhe/pdb |
Descriptor | CREB-binding protein, (6S)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(3R)-1-methylsulfonylpyrrolidin-3-yl]benzimidazol-2-yl]-1-(3-fluoranyl-4-methoxy-phenyl)piperidin-2-one, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | histone acetyltransferase, cbp, bromodomain, protein binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 33007.98 |
Authors | |
Primary citation | Xu, H.,Luo, G.,Wu, T.,Hu, J.,Wang, C.,Wu, X.,Zhang, Y.,Xu, Y.,Xiang, Q. Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain Biochem.Biophys.Res.Commun., 623:17-22, 2022 Cited by DOI: 10.1016/j.bbrc.2022.07.021PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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