7XH4

Dihydrofolate Reductase-like Protein SacH in safracin biosynthesis complex with safracin A

7XH4 の概要

• エントリーDOI: 10.2210/pdb7xh4/pdb
• 分子名称: Uncharacterized protein sfcH, Safracin A, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: reductase, safracin biosynthesis, self-resistance, complex structure., oxidoreductase
• 由来する生物種: Pseudomonas fluorescens
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23288.87

構造登録者

Ma, X.,Shao, N.,Zhang, Y.,Yang, D.,Ma, M.,Tang, G. (登録日: 2022-04-07, 公開日: 2023-02-08, 最終更新日: 2023-11-29)

• 主引用文献: Shao, N.,Ma, X.,Zhang, Y.Y.,Yang, D.,Ma, M.,Tang, G.L.; Dihydrofolate reductase-like protein inactivates hemiaminal pharmacophore for self-resistance in safracin biosynthesis.; Acta Pharm Sin B, 13:1318-1325, 2023; PubMed: 36970210; DOI: 10.1016/j.apsb.2022.10.005

実験手法

X-RAY DIFFRACTION (2.2 Å)