7XB4

Crystal structure of SARS-Cov-2 main protease D48N mutant in complex with PF07321332

Summary for 7XB4

• Entry DOI: 10.2210/pdb7xb4/pdb
• Descriptor: Replicase polyprotein 1a, (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide (3 entities in total)
• Functional Keywords: viral protein-inhibitor complex, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 68652.21

Authors

Hu, X.H.,Li, J.,Zhang, J. (deposition date: 2022-03-20, release date: 2023-03-22, Last modification date: 2023-11-29)

• Primary citation: Hu, X.H.,Li, J.,Zhang, J.; Crystal structure of SARS-Cov-2 main protease D48N mutant in complex with PF07321332; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.07 Å)