7X9P

Crystal structure of human STING complexed with compound BSP17

Summary for 7X9P

• Entry DOI: 10.2210/pdb7x9p/pdb
• Descriptor: Stimulator of interferon genes protein, 4-[6-methoxy-5-[3-[[6-methoxy-2-(4-oxidanyl-4-oxidanylidene-butanoyl)-1-benzoselenophen-5-yl]oxy]propoxy]-1-benzoselenophen-2-yl]-4-oxidanylidene-butanoic acid (3 entities in total)
• Functional Keywords: sting agonists, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 26714.75

Authors

Pan, L.,Guan, X.,Feng, X.,Li, Z.,Bian, J. (deposition date: 2022-03-15, release date: 2023-03-22, Last modification date: 2023-11-29)

• Primary citation: Feng, X.,Pan, L.,Qiang, Z.,Liu, D.,Guan, X.,Feng, L.,Song, B.,Xu, X.,Tan, N.,Ma, Y.,Li, Z.,Wang, Z.,BIan, J.; Discovery of Selenium-containing STING agonists as orally available anti tumor agents; To be published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)