7WY2

Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 F87A Mutant Haem Domain with N-Enanthyl-L-Prolyl-L-Phenylalanine in complex with Styrene

7WY2 の概要

• エントリーDOI: 10.2210/pdb7wy2/pdb
• 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, Oxomolybdenum Mesoporphyrin IX, (2S)-2-[[(2S)-1-heptylpyrrolidin-2-yl]carbonylamino]-3-phenyl-propanoic acid, ... (7 entities in total)
• 機能のキーワード: monooxygenase, oxidoreductase
• 由来する生物種: Priestia megaterium
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 108091.85

構造登録者

Suzuki, K.,Stanfield, J.K.,Shisaka, Y.,Omura, K.,Kasai, C.,Sugimoto, H.,Shoji, O. (登録日: 2022-02-15, 公開日: 2023-01-04, 最終更新日: 2023-11-29)

• 主引用文献: Suzuki, K.,Stanfield, J.K.,Omura, K.,Shisaka, Y.,Ariyasu, S.,Kasai, C.,Aiba, Y.,Sugimoto, H.,Shoji, O.; A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations.; Angew.Chem.Int.Ed.Engl., 62:e202215706-e202215706, 2023; PubMed: 36519803; DOI: 10.1002/anie.202215706

実験手法

X-RAY DIFFRACTION (1.45 Å)