7WX2
CBP-BrD complexed with NEO2734
Summary for 7WX2
Entry DOI | 10.2210/pdb7wx2/pdb |
Descriptor | CREB-binding protein, 1,3-dimethyl-5-[2-(oxan-4-yl)-3-[2-(trifluoromethyloxy)ethyl]benzimidazol-5-yl]pyridin-2-one (3 entities in total) |
Functional Keywords | cbp, bromodomain, neo2734, complex, protein binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 14853.99 |
Authors | |
Primary citation | Ji, D.,Shang, G.,Wei, E.,Jia, Y.,Wang, C.,Zhang, Q.,Zeng, L. Targeting CDCP1 gene transcription coactivated by BRD4 and CBP/p300 in castration-resistant prostate cancer. Oncogene, 41:3251-3262, 2022 Cited by PubMed: 35513563DOI: 10.1038/s41388-022-02327-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.24 Å) |
Structure validation
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