7WVV
Cryo-EM structure of the human formyl peptide receptor 2 in complex with fMLFII and Gi2
Summary for 7WVV
Entry DOI | 10.2210/pdb7wvv/pdb |
EMDB information | 32859 |
Descriptor | FME-LEU-PHE-ILE-ILE, Soluble cytochrome b562,N-formyl peptide receptor 2, Guanine nucleotide-binding protein G(i) subunit alpha-2, ... (5 entities in total) |
Functional Keywords | g protein-coupled receptor, formyl peptide receptor, fpr2, fmlfii, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 144482.57 |
Authors | |
Primary citation | Zhu, Y.,Lin, X.,Zong, X.,Han, S.,Wang, M.,Su, Y.,Ma, L.,Chu, X.,Yi, C.,Zhao, Q.,Wu, B. Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin. Nat Commun, 13:1775-1775, 2022 Cited by PubMed: 35365641DOI: 10.1038/s41467-022-29361-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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