7WSJ

Crystal structure of the tandem B-box domain of Arabidopsis thaliana CONSTANS

7WSJ の概要

• エントリーDOI: 10.2210/pdb7wsj/pdb
• 分子名称: Zinc finger protein CONSTANS, ZINC ION (3 entities in total)
• 機能のキーワード: tandem b-box, zn-coordinating motif, photoperiodic flowering, plant protein
• 由来する生物種: Arabidopsis thaliana (thale cress)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 36822.20

構造登録者

Dahal, P.,Pathak, D.,Kwon, E.,Kim, D.Y. (登録日: 2022-01-29, 公開日: 2022-03-02, 最終更新日: 2024-05-29)

主引用文献

Dahal, P.,Kwon, E.,Pathak, D.,Kim, D.Y.
Crystal structure of a tandem B-box domain from Arabidopsis CONSTANS.
Biochem.Biophys.Res.Commun., 599:38-42, 2022

PubMed Abstract: CONSTANS is a central protein in the regulation of photoperiodic flowering, which is expressed in response to day length and promotes the expression of Flowering Locus T. The tandem B-box domain in CONSTANS mediates interactions with various proteins to regulate the expression of Flowering Locus T. Although most plants, including Arabidopsis, have multiple B-box proteins, their B-box structures have not been elucidated. Here, we report the crystal structure of a tandem B-box domain from Arabidopsis CONSTANS. The crystal structure shows that each B-box adopts a canonical B-box fold and coordinates two zinc atoms. Furthermore, the crystal structure reveals that the B-box domain has a unique structure that distinguishes it from animal B-boxes at the monomer and dimer level.

PubMed: 35168062
DOI: 10.1016/j.bbrc.2022.02.025

実験手法

X-RAY DIFFRACTION (2.4 Å)