7WPH

SARS-CoV2 RBD bound to Fab06

7WPH の概要

• エントリーDOI: 10.2210/pdb7wph/pdb
• 分子名称: Spike protein S1, FAB06 light chain, Fab06 heavy chain, ... (5 entities in total)
• 機能のキーワード: sars-cov2 rbd, antibody, protein binding, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV,SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 155649.28

構造登録者

Lin, J.Q.,El Sahili, A.,Lescar, J. (登録日: 2022-01-23, 公開日: 2022-03-30, 最終更新日: 2023-11-29)

• 主引用文献: Ku, Z.,Xie, X.,Lin, J.,Gao, P.,Wu, B.,El Sahili, A.,Su, H.,Liu, Y.,Ye, X.,Tan, E.Y.,Li, X.,Fan, X.,Goh, B.C.,Xiong, W.,Boyd, H.,Muruato, A.E.,Deng, H.,Xia, H.,Zou, J.,Kalveram, B.K.,Menachery, V.D.,Zhang, N.,Lescar, J.,Shi, P.Y.,An, Z.; Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth.; Nat Commun, 13:5552-5552, 2022; PubMed: 36138032; DOI: 10.1038/s41467-022-33284-y

実験手法

X-RAY DIFFRACTION (2.89 Å)