7WON

Cryo-EM structure of SARS-CoV-2 S2P trimer in complex with neutralizing antibody VacW-209 (local refinement)

7WON の概要

• エントリーDOI: 10.2210/pdb7won/pdb
• EMDBエントリー: 32652
• 分子名称: Spike protein S1, VacW-209 light chain, VacW-209 heavy chain, ... (4 entities in total)
• 機能のキーワード: sars-cov-2, spike, neutralizing antibody, cryo-em, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 47743.95

構造登録者

Zheng, Q.,Sun, H.,Ju, B.,Zhang, Z.,Li, S.,Xia, N. (登録日: 2022-01-22, 公開日: 2022-07-13, 最終更新日: 2025-07-02)

• 主引用文献: Ju, B.,Zheng, Q.,Guo, H.,Fan, Q.,Li, T.,Song, S.,Sun, H.,Shen, S.,Zhou, X.,Xue, W.,Cui, L.,Zhou, B.,Li, S.,Xia, N.,Zhang, Z.; Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209.; Cell Res., 32:491-494, 2022; PubMed: 35260792; DOI: 10.1038/s41422-022-00638-6

実験手法

ELECTRON MICROSCOPY (3.9 Å)