7WO1
Discovery of SARS-CoV-2 3CLpro peptidomimetic inhibitors through H41-specific protein-ligand interactions
Summary for 7WO1
Entry DOI | 10.2210/pdb7wo1/pdb |
Descriptor | 3C-like proteinase, N-[(2S)-3-methyl-1-[[(2S)-4-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]cyclohexanecarboxamide (3 entities in total) |
Functional Keywords | sars-cov-2 main protease, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 1 |
Total formula weight | 34318.20 |
Authors | |
Primary citation | Wang, Y.,Xu, B.,Ma, S.,Wang, H.,Shang, L.,Zhu, C.,Ye, S. Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions. Int J Mol Sci, 23:-, 2022 Cited by PubMed: 35216507DOI: 10.3390/ijms23042392 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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