7WM0

Cryo-EM structure of the Omicron RBD in complex with 35B5 Fab( local refinement of the RBD and 35B5 Fab)

Summary for 7WM0

• Entry DOI: 10.2210/pdb7wm0/pdb
• EMDB information: 32596
• Descriptor: Spike glycoprotein, Light chain of 35B5 Fab, Heavy chain of 35B5 Fab, ... (4 entities in total)
• Functional Keywords: immune system, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 3
• Total formula weight: 191852.31

Authors

Wang, X.,Zhu, Y. (deposition date: 2022-01-14, release date: 2022-08-17, Last modification date: 2024-11-06)

• Primary citation: Wang, X.,Chen, X.,Tan, J.,Yue, S.,Zhou, R.,Xu, Y.,Lin, Y.,Yang, Y.,Zhou, Y.,Deng, K.,Chen, Z.,Ye, L.,Zhu, Y.; 35B5 antibody potently neutralizes SARS-CoV-2 Omicron by disrupting the N-glycan switch via a conserved spike epitope; Cell Host Microbe, 30:887-, 2022; DOI: 10.1016/j.chom.2022.03.035

Experimental method

ELECTRON MICROSCOPY (3.35 Å)