7WJ7
Crystal Structure of the Kinase Domain with Adenosine of a Class III Lanthipeptide Synthetase CurKC
Summary for 7WJ7
Entry DOI | 10.2210/pdb7wj7/pdb |
Descriptor | Serine/threonine protein kinase, 2-(6-AMINO-OCTAHYDRO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL (3 entities in total) |
Functional Keywords | lanthipeptide synthetase, class iii, curkc, curvopeptin, biosynthetic protein |
Biological source | Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 / NCIMB 10081 / Henssen B9) |
Total number of polymer chains | 2 |
Total formula weight | 60891.09 |
Authors | |
Primary citation | Huang, S.,Wang, Y.,Cai, C.,Xiao, X.,Liu, S.,Ma, Y.,Xie, X.,Liang, Y.,Chen, H.,Zhu, J.,Hegemann, J.D.,Yao, H.,Wei, W.,Wang, H. Discovery of a Unique Structural Motif in Lanthipeptide Synthetases for Substrate Binding and Interdomain Interactions. Angew.Chem.Int.Ed.Engl., 61:e202211382-e202211382, 2022 Cited by PubMed: 36102578DOI: 10.1002/anie.202211382 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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