7WIT
Structure of SUR1 in complex with mitiglinide
Summary for 7WIT
Entry DOI | 10.2210/pdb7wit/pdb |
EMDB information | 32535 |
Descriptor | ATP-sensitive inward rectifier potassium channel 11,ATP-binding cassette sub-family C member 8 isoform X1, ADENOSINE-5'-TRIPHOSPHATE, (2S)-4-[(3aR,7aS)-1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl]-4-oxidanylidene-2-(phenylmethyl)butanoic acid (3 entities in total) |
Functional Keywords | sur1, katp, channel, mitiglinide, membrane protein |
Biological source | Bos taurus (cattle) More |
Total number of polymer chains | 1 |
Total formula weight | 160262.43 |
Authors | Chen, L.,Wang, M.M. (deposition date: 2022-01-04, release date: 2022-11-16, Last modification date: 2024-06-26) |
Primary citation | Wang, M.M.,Wu, J.X.,Chen, L. Structural Insights Into the High Selectivity of the Anti-Diabetic Drug Mitiglinide Front Pharmacol, 13:929684-929684, 2022 Cited by PubMed: 35847046DOI: 10.3389/fphar.2022.929684 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.21 Å) |
Structure validation
Download full validation report