7WGD

X-ray structure of thermostabilized Drosophila dopamine transporter with GABA transporter1-like substitutions in the binding site, in substrate-free form.

7WGD の概要

• エントリーDOI: 10.2210/pdb7wgd/pdb
• 分子名称: Sodium-dependent dopamine transporter, Antibody fragment (9D5) Light Chain, Antibody fragment (9D5) heavy chain, ... (8 entities in total)
• 機能のキーワード: neurotransmitter transporter, antibody fragment, gaba transporter, membrane protein
• 由来する生物種: Drosophila melanogaster (fruit fly); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 108025.42

構造登録者

Joseph, D.,Penmatsa, A. (登録日: 2021-12-28, 公開日: 2022-06-29, 最終更新日: 2023-11-29)

• 主引用文献: Joseph, D.,Nayak, S.R.,Penmatsa, A.; Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter.; Embo J., 41:e110735-e110735, 2022; PubMed: 35796008; DOI: 10.15252/embj.2022110735

実験手法

X-RAY DIFFRACTION (3.2 Å)