7WFW
Apo human Nav1.8
Summary for 7WFW
Entry DOI | 10.2210/pdb7wfw/pdb |
EMDB information | 32476 |
Descriptor | Sodium channel protein type 10 subunit alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | voltage-gated sodium channel, nav, activation, selectivity, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 231790.53 |
Authors | Yan, N.,Pan, X.J.,Huang, X.S.,Huang, G.X. (deposition date: 2021-12-27, release date: 2022-08-03, Last modification date: 2022-09-21) |
Primary citation | Huang, X.,Jin, X.,Huang, G.,Huang, J.,Wu, T.,Li, Z.,Chen, J.,Kong, F.,Pan, X.,Yan, N. Structural basis for high-voltage activation and subtype-specific inhibition of human Na v 1.8. Proc.Natl.Acad.Sci.USA, 119:e2208211119-e2208211119, 2022 Cited by PubMed: 35858452DOI: 10.1073/pnas.2208211119 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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