7WDG

Crystal structure of the P450 BM3 heme domain mutant F87L in complex with N-imidazolyl-hexanoyl-L-phenylalanine, phenol and hydroxylamine

7WDG の概要

• エントリーDOI: 10.2210/pdb7wdg/pdb
• 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, HYDROXYAMINE, ... (6 entities in total)
• 機能のキーワード: dual-functional small molecule, p450 heme domain, complex, oxidoreductase
• 由来する生物種: Priestia megaterium
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 109970.95

構造登録者

Jiang, Y.,Dong, S.,Feng, Y.,Cong, Z. (登録日: 2021-12-21, 公開日: 2022-12-28, 最終更新日: 2023-11-29)

• 主引用文献: Wang, X.,Lin, X.,Jiang, Y.,Qin, X.,Ma, N.,Yao, F.,Dong, S.,Liu, C.,Feng, Y.,Jin, L.,Xian, M.,Cong, Z.; Engineering Cytochrome P450BM3 Enzymes for Direct Nitration of Unsaturated Hydrocarbons.; Angew.Chem.Int.Ed.Engl., 62:e202217678-e202217678, 2023; PubMed: 36660956; DOI: 10.1002/anie.202217678

実験手法

X-RAY DIFFRACTION (2.07 Å)