7WD3

Cryo-EM structure of Drg1 hexamer treated with ATP and benzo-diazaborine

Summary for 7WD3

• Entry DOI: 10.2210/pdb7wd3/pdb
• EMDB information: 32403
• Descriptor: ATPase family gene 2 protein, ADENOSINE-5'-TRIPHOSPHATE, 2-(TOLUENE-4-SULFONYL)-2H-BENZO[D][1,2,3]DIAZABORININ-1-OL (3 entities in total)
• Functional Keywords: drg1, ribosome, atp-binding protein
• Biological source: Saccharomyces cerevisiae (baker's yeast)
• Total number of polymer chains: 6
• Total formula weight: 500382.11

Authors

Ma, C.Y.,Wu, D.M.,Chen, Q.,Gao, N. (deposition date: 2021-12-21, release date: 2022-12-14, Last modification date: 2024-06-26)

• Primary citation: Ma, C.,Wu, D.,Chen, Q.,Gao, N.; Structural dynamics of AAA + ATPase Drg1 and mechanism of benzo-diazaborine inhibition.; Nat Commun, 13:6765-6765, 2022; PubMed: 36351914; DOI: 10.1038/s41467-022-34511-2

Experimental method

ELECTRON MICROSCOPY (3.8 Å)