7WC5

Crystal structure of serotonin 2A receptor in complex with psilocin

Summary for 7WC5

• Entry DOI: 10.2210/pdb7wc5/pdb
• Descriptor: 5-hydroxytryptamine receptor 2A, MAGNESIUM ION, CHOLESTEROL, ... (5 entities in total)
• Functional Keywords: serotonin 2a receptor, psilocin, psilocybin, 5-ht, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 44127.76

Authors

Cao, D.,Yu, J.,Wang, H.,Luo, Z.,Liu, X.,He, L.,Qi, J.,Fan, L.,Tang, L.,Chen, Z.,Li, J.,Cheng, J.,Wang, S. (deposition date: 2021-12-18, release date: 2022-01-26, Last modification date: 2023-11-29)

• Primary citation: Cao, D.,Yu, J.,Wang, H.,Luo, Z.,Liu, X.,He, L.,Qi, J.,Fan, L.,Tang, L.,Chen, Z.,Li, J.,Cheng, J.,Wang, S.; Structure-based discovery of nonhallucinogenic psychedelic analogs.; Science, 375:403-411, 2022; PubMed: 35084960; DOI: 10.1126/science.abl8615

Experimental method

X-RAY DIFFRACTION (3.2 Å)