7W6M

Cryo-EM map of PEDV (Pintung 52) S protein with all three protomers in the D0-down conformation determined in situ on intact viral particles.

7W6M の概要

• エントリーDOI: 10.2210/pdb7w6m/pdb
• EMDBエントリー: 32329
• 分子名称: Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: pedv, spike, glycoprotein, viral protein
• 由来する生物種: Porcine epidemic diarrhea virus
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 494470.26

構造登録者

Hsu, S.T.D.,Draczkowski, P.,Wang, Y.S. (登録日: 2021-12-02, 公開日: 2022-08-03, 最終更新日: 2022-09-14)

• 主引用文献: Huang, C.Y.,Draczkowski, P.,Wang, Y.S.,Chang, C.Y.,Chien, Y.C.,Cheng, Y.H.,Wu, Y.M.,Wang, C.H.,Chang, Y.C.,Chang, Y.C.,Yang, T.J.,Tsai, Y.X.,Khoo, K.H.,Chang, H.W.,Hsu, S.D.; In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.; Nat Commun, 13:4877-4877, 2022; PubMed: 35986008; DOI: 10.1038/s41467-022-32588-3

実験手法

ELECTRON MICROSCOPY (4.7 Å)