7W23

Structure of the M. tuberculosis HtrA S363A mutant

7W23 の概要

• エントリーDOI: 10.2210/pdb7w23/pdb
• 分子名称: Probable serine protease HtrA1 (2 entities in total)
• 機能のキーワード: hydrolase, htra family of serine protease, chymotrypsin-like, periplasm, protein quality control and signal transduction.
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32506.39

構造登録者

Gupta, A.K.,Gopal, B. (登録日: 2021-11-21, 公開日: 2022-11-23, 最終更新日: 2023-11-29)

• 主引用文献: Gupta, A.K.,Singh, K.,Patidar, Y.,Sharma, R.,Sardesai, A.A.,Reddy, G.,Gopal, B.; Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.; Acs Chem.Biol., 18:1487-1499, 2023; PubMed: 37319329; DOI: 10.1021/acschembio.2c00921

実験手法

X-RAY DIFFRACTION (1.9 Å)