7W07

Itaconate inducible LysR-Type Transcriptional regulator (ITCR) in complex with itaconate, Space group C121.

Summary for 7W07

• Entry DOI: 10.2210/pdb7w07/pdb
• Descriptor: Transcriptional regulator, LysR family, 2-methylidenebutanedioic acid, SULFATE ION, ... (4 entities in total)
• Functional Keywords: lttr, itcr, itaconate, transcription
• Biological source: Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
• Total number of polymer chains: 1
• Total formula weight: 32484.21

Authors

Sun, P.K.,Wang, B.,Li, X.J. (deposition date: 2021-11-17, release date: 2022-10-26, Last modification date: 2023-11-29)

• Primary citation: Sun, P.,Zhang, Z.,Wang, B.,Liu, C.,Chen, C.,Liu, P.,Li, X.; A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages.; Nat Commun, 13:6562-6562, 2022; PubMed: 36333306; DOI: 10.1038/s41467-022-34306-5

Experimental method

X-RAY DIFFRACTION (1.48 Å)