7VWE

Human peroxisome proliferator-activated receptor (PPAR) delta ligand binding domain in complex with a synthetic partial agonist JK122

7VWE の概要

• エントリーDOI: 10.2210/pdb7vwe/pdb
• 分子名称: Peroxisome proliferator-activated receptor delta, heptyl beta-D-glucopyranoside, 5-[4-butoxy-3-[[[2-fluoranyl-4-(trifluoromethyl)phenyl]carbonylamino]methyl]phenyl]-4,6-dimethyl-pyridine-3-carboxylic acid, ... (4 entities in total)
• 機能のキーワード: nuclear receptor, protein-ligand complex, ppar, transcription
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 64648.98

構造登録者

Oyama, T.,Miyachi, H. (登録日: 2021-11-10, 公開日: 2022-02-09, 最終更新日: 2023-11-29)

• 主引用文献: Oyama, T.,Takiguchi, K.,Miyachi, H.; Crystal structures of the ligand-binding domain of human peroxisome proliferator-activated receptor delta in complexes with phenylpropanoic acid derivatives and a pyridine carboxylic acid derivative.; Acta Crystallogr.,Sect.F, 78:81-87, 2022; DOI: 10.1107/S2053230X22000449

実験手法

X-RAY DIFFRACTION (3 Å)