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7VVP

Crystal structure of SARS-Cov-2 main protease in complex with PF07304814

Summary for 7VVP
Entry DOI10.2210/pdb7vvp/pdb
Descriptor3C-like proteinase, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate (3 entities in total)
Functional Keywordsviral protein-inhibitor complex, viral protein/inhibitor
Biological sourceSevere acute respiratory syndrome coronavirus 2
Total number of polymer chains2
Total formula weight66213.48
Authors
Zhou, X.L.,Zhong, F.L.,Lin, C.,Zeng, P.,Zhang, J.,Li, J. (deposition date: 2021-11-07, release date: 2022-08-24, Last modification date: 2023-11-29)
Primary citationLi, J.,Lin, C.,Zhou, X.,Zhong, F.,Zeng, P.,McCormick, P.J.,Jiang, H.,Zhang, J.
Structural Basis of Main Proteases of Coronavirus Bound to Drug Candidate PF-07304814
J.Mol.Biol., 434:167706-, 2022
Cited by
DOI: 10.1016/j.jmb.2022.167706
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.97 Å)
Structure validation

221051

数据于2024-06-12公开中

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