7VVM
PTH-bound human PTH1R in complex with Gs (class3)
Summary for 7VVM
Entry DOI | 10.2210/pdb7vvm/pdb |
EMDB information | 32144 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | g protein-coupled receptor, membrane protein, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 163953.59 |
Authors | Kobayashi, K.,Kusakizako, T.,Miyauchi, H.,Tomita, A.,Kobayashi, K.,Shihoya, W.,Yamashita, K.,Nishizawa, T.,Kato, H.E.,Nureki, O. (deposition date: 2021-11-06, release date: 2022-08-03, Last modification date: 2023-02-15) |
Primary citation | Kobayashi, K.,Kawakami, K.,Kusakizako, T.,Miyauchi, H.,Tomita, A.,Kobayashi, K.,Shihoya, W.,Yamashita, K.,Nishizawa, T.,Kato, H.E.,Inoue, A.,Nureki, O. Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82:3468-3483.e5, 2022 Cited by PubMed: 35932760DOI: 10.1016/j.molcel.2022.07.003 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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