7VO5

Pimaricin type I PKS thioesterase domain (holo Pim TE)

Summary for 7VO5

• Entry DOI: 10.2210/pdb7vo5/pdb
• Descriptor: ScnS4, (1R,3S,5E,7S,11R,13E,15E,17E,19E,21R,23S,24R,25S)-11,24-dimethyl-1,3,7,21,25-pentakis(oxidanyl)-10,27-dioxabicyclo[21.3.1]heptacosa-5,13,15,17,19-pentaen-9-one (3 entities in total)
• Functional Keywords: thioesterase, type i thioesterase, pimaricin, polyketide synthase thioesterase domain, biosynthetic protein
• Biological source: Streptomyces chattanoogensis
• Total number of polymer chains: 1
• Total formula weight: 31391.56

Authors

Bai, L.,Zhou, Y. (deposition date: 2021-10-12, release date: 2022-01-19, Last modification date: 2023-11-29)

• Primary citation: Zhou, Y.,Tao, W.,Qi, Z.,Wei, J.,Shi, T.,Kang, Q.,Zheng, J.,Zhao, Y.,Bai, L.; Structural and Mechanistic Insights into Chain Release of the Polyene PKS Thioesterase Domain; Acs Catalysis, 12:762-776, 2022; DOI: 10.1021/acscatal.1c04991

Experimental method

X-RAY DIFFRACTION (2.4 Å)