7VNE

Structure of the SARS-CoV-2 spike glycoprotein in complex with a human single domain antibody n3113.1 (UUU-state)

7VNE の概要

• エントリーDOI: 10.2210/pdb7vne/pdb
• EMDBエントリー: 32040
• 分子名称: Spike glycoprotein, n3113.1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: sars-cov-2, nanobody, antiviral protein, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 460051.25

構造登録者

Yang, Z.,Wang, Y.,Kong, Y.,Jin, Y.,Wu, Y.,Ying, T. (登録日: 2021-10-10, 公開日: 2021-11-24)

• 主引用文献: Yang, Z.,Wang, Y.,Jin, Y.,Zhu, Y.,Wu, Y.,Li, C.,Kong, Y.,Song, W.,Tian, X.,Zhan, W.,Huang, A.,Zhou, S.,Xia, S.,Tian, X.,Peng, C.,Chen, C.,Shi, Y.,Hu, G.,Du, S.,Wang, Y.,Xie, Y.,Jiang, S.,Lu, L.,Sun, L.,Song, Y.,Ying, T.; A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants.; Signal Transduct Target Ther, 6:378-378, 2021; PubMed: 34732694; DOI: 10.1038/s41392-021-00810-1

実験手法

ELECTRON MICROSCOPY (3.5 Å)