7VNB

Crystal structure of the SARS-CoV-2 RBD in complex with a human single domain antibody n3113

7VNB の概要

• エントリーDOI: 10.2210/pdb7vnb/pdb
• 分子名称: n3113, Spike protein S1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: sars-cov-2, nanobody, viral protein
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38150.67

構造登録者

Yang, Z.,Wang, Y.,Kong, Y.,Jin, Y.,Wu, Y.,Ying, T. (登録日: 2021-10-10, 公開日: 2021-11-24, 最終更新日: 2023-11-29)

• 主引用文献: Yang, Z.,Wang, Y.,Jin, Y.,Zhu, Y.,Wu, Y.,Li, C.,Kong, Y.,Song, W.,Tian, X.,Zhan, W.,Huang, A.,Zhou, S.,Xia, S.,Tian, X.,Peng, C.,Chen, C.,Shi, Y.,Hu, G.,Du, S.,Wang, Y.,Xie, Y.,Jiang, S.,Lu, L.,Sun, L.,Song, Y.,Ying, T.; A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants.; Signal Transduct Target Ther, 6:378-378, 2021; PubMed: 34732694; DOI: 10.1038/s41392-021-00810-1

実験手法

X-RAY DIFFRACTION (2.27 Å)