7V8S
Crystal structure of cyclohexanone monooxygenase from T. municipale mutant L437T complexed with NADP+ and FAD in space group of P1211
Summary for 7V8S
Entry DOI | 10.2210/pdb7v8s/pdb |
Descriptor | Cyclohexanone Monooxygenase from Thermocrispum municipale, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
Functional Keywords | cyclohexanone monooxygenase, directed evolution, regioselectivity, flavoprotein |
Biological source | Thermocrispum municipale |
Total number of polymer chains | 2 |
Total formula weight | 123539.10 |
Authors | |
Primary citation | Dong, Y.J.,Li, T.,Zhang, S.Q.,Sanchis, J.,Yin, H.,Ren, J.,Sheng, X.,Li, G.Y.,Reetz, M.T. Biocatalytic Baeyer-Villiger Reactions: Uncovering the Source of Regioselectivity at Each Evolutionary Stage of a Mutant with Scrutiny of Fleeting Chiral Intermediates. Acs Catalysis, 12:3669-3680, 2022 Cited by DOI: 10.1021/acscatal.2c00415PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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