7V8R

Crystal structure of cyclohexanone monooxygenase from T. municipale mutant L437T complexed with NADP+ and FAD in space group of C2221

Summary for 7V8R

• Entry DOI: 10.2210/pdb7v8r/pdb
• Descriptor: Cyclohexanone Monooxygenase from Thermocrispum municipale, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (7 entities in total)
• Functional Keywords: cyclohexanone monooxygenase, directed evolution, regioselectivity, flavoprotein
• Biological source: Thermocrispum municipale
• Total number of polymer chains: 1
• Total formula weight: 62337.64

Authors

Li, T.,Li, G.Y.,Yin, H. (deposition date: 2021-08-23, release date: 2022-07-06, Last modification date: 2023-11-29)

• Primary citation: Dong, Y.J.,Li, T.,Zhang, S.Q.,Sanchis, J.,Yin, H.,Ren, J.,Sheng, X.,Li, G.Y.,Reetz, M.T.; Biocatalytic Baeyer-Villiger Reactions: Uncovering the Source of Regioselectivity at Each Evolutionary Stage of a Mutant with Scrutiny of Fleeting Chiral Intermediates.; Acs Catalysis, 12:3669-3680, 2022; DOI: 10.1021/acscatal.2c00415

Experimental method

X-RAY DIFFRACTION (1.764 Å)