7V8O

Crystal structure of cyclohexanone monooxygenase from T. municipale mutant L437T complexed with NADP+ and FAD in space group of P21221

7V8O の概要

• エントリーDOI: 10.2210/pdb7v8o/pdb
• 分子名称: Cyclohexanone Monooxygenase from Thermocrispum municipale, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (7 entities in total)
• 機能のキーワード: cyclohexanone monooxygenase, directed evolution, regioselectivity, flavoprotein
• 由来する生物種: Thermocrispum municipale
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 123615.33

構造登録者

Li, T.,Li, G.Y.,Yin, H. (登録日: 2021-08-23, 公開日: 2022-07-06, 最終更新日: 2023-11-29)

• 主引用文献: Dong, Y.J.,Li, T.,Zhang, S.Q.,Sanchis, J.,Yin, H.,Ren, J.,Sheng, X.,Li, G.Y.,Reetz, M.T.; Biocatalytic Baeyer-Villiger Reactions: Uncovering the Source of Regioselectivity at Each Evolutionary Stage of a Mutant with Scrutiny of Fleeting Chiral Intermediates.; Acs Catalysis, 12:3669-3680, 2022; DOI: 10.1021/acscatal.2c00415

実験手法

X-RAY DIFFRACTION (2.72 Å)