7V7M

crystal structure of SARS-CoV-2 3CL protease

Summary for 7V7M

• Entry DOI: 10.2210/pdb7v7m/pdb
• Descriptor: 3C-like proteinase (2 entities in total)
• Functional Keywords: protease, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• Total number of polymer chains: 1
• Total formula weight: 33825.55

Authors

Yi, Y.,Zhang, M.,Ye, M. (deposition date: 2021-08-21, release date: 2022-06-29, Last modification date: 2024-01-17)

• Primary citation: Yi, Y.,Zhang, M.,Xue, H.,Yu, R.,Bao, Y.O.,Kuang, Y.,Chai, Y.,Ma, W.,Wang, J.,Shi, X.,Li, W.,Hong, W.,Li, J.,Muturi, E.,Wei, H.,Wlodarz, J.,Roszak, S.,Qiao, X.,Yang, H.,Ye, M.; Schaftoside inhibits 3CL pro and PL pro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19.; Acta Pharm Sin B, 12:4154-4164, 2022; PubMed: 35968270; DOI: 10.1016/j.apsb.2022.07.017

Experimental method

X-RAY DIFFRACTION (2.08 Å)