7V6X

Crystal structure of HPPD complexed with Y18556

7V6X の概要

• エントリーDOI: 10.2210/pdb7v6x/pdb
• 分子名称: 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, 5-methyl-3-[(2-methylphenyl)methyl]-6-[(1~{R},2~{S})-2-oxidanyl-6-oxidanylidene-cyclohexyl]carbonyl-1,2,3-benzotriazin-4-one, ... (4 entities in total)
• 機能のキーワード: complex, inhibitor, oxidoreductase
• 由来する生物種: Arabidopsis thaliana (Mouse-ear cress)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46417.11

構造登録者

Lin, H.Y.,Yang, G.F. (登録日: 2021-08-20, 公開日: 2022-08-24, 最終更新日: 2023-11-29)

• 主引用文献: Yan, Y.C.,Wu, W.,Huang, G.Y.,Yang, W.C.,Chen, Q.,Qu, R.Y.,Lin, H.Y.,Yang, G.F.; Pharmacophore-Oriented Discovery of Novel 1,2,3-Benzotriazine-4-one Derivatives as Potent 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors.; J.Agric.Food Chem., 70:6644-6657, 2022; PubMed: 35618678; DOI: 10.1021/acs.jafc.2c01507

実験手法

X-RAY DIFFRACTION (1.8 Å)