7UZD

Structure of the SARS-CoV-2 RBD in complex with the mouse antibody Fab fragment, HSW-2

7UZD の概要

• エントリーDOI: 10.2210/pdb7uzd/pdb
• 分子名称: Spike protein S1, HSW-2 Fab heavy chain, HSW-2 Fab light chain, ... (4 entities in total)
• 機能のキーワード: immune system, neutralizing antibody, immune system-viral protein complex, immune system/viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 74730.48

構造登録者

Fan, C.,Bjorkman, P.J. (登録日: 2022-05-08, 公開日: 2023-01-11, 最終更新日: 2023-10-25)

• 主引用文献: Fan, C.,Cohen, A.A.,Park, M.,Hung, A.F.,Keeffe, J.R.,Gnanapragasam, P.N.P.,Lee, Y.E.,Gao, H.,Kakutani, L.M.,Wu, Z.,Kleanthous, H.,Malecek, K.E.,Williams, J.C.,Bjorkman, P.J.; Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.; Immunity, 55:2419-2435.e10, 2022; PubMed: 36370711; DOI: 10.1016/j.immuni.2022.10.019

実験手法

X-RAY DIFFRACTION (3 Å)