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7UZ2

Structure of beta-glycosidase from Sulfolobus solfataricus in complex with C5a-fluoro-valienide.

Summary for 7UZ2
Entry DOI10.2210/pdb7uz2/pdb
DescriptorBeta-galactosidase, (1R,2S,3R,4R)-5-fluoro-6-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol (3 entities in total)
Functional Keywordscovalent inhibition, glycoside hydrolase, hydrolase
Biological sourceSaccharolobus solfataricus
Total number of polymer chains2
Total formula weight114041.25
Authors
Danby, P.M.,Jeong, A.,Sim, L.,Sweeney, R.P.,Wardman, J.F.,Geissner, A.,Worrall, L.J.,Strynadka, N.C.J.,Withers, S.G. (deposition date: 2022-05-08, release date: 2023-04-05, Last modification date: 2023-10-25)
Primary citationDanby, P.M.,Jeong, A.,Sim, L.,Sweeney, R.P.,Wardman, J.F.,Karimi, R.,Geissner, A.,Worrall, L.J.,Reid, J.P.,Strynadka, N.C.J.,Withers, S.G.
Vinyl Halide-Modified Unsaturated Cyclitols are Mechanism-Based Glycosidase Inhibitors.
Angew.Chem.Int.Ed.Engl., 62:e202301258-e202301258, 2023
Cited by
PubMed: 36940280
DOI: 10.1002/anie.202301258
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.83 Å)
Structure validation

221051

건을2024-06-12부터공개중

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