7UXR

Crystal structure of the BtTir TIR domain

Summary for 7UXR

Entry DOI	10.2210/pdb7uxr/pdb
Descriptor	TIR domain protein (2 entities in total)
Functional Keywords	cadpr isomer, nad+, bacterial tir, hydrolase
Biological source	Bacteroides thetaiotaomicron
Total number of polymer chains	2
Total formula weight	39792.34
Authors	Shi, Y.,Masic, V.,Mosaiab, T.,Vasquez, E.,Ve, T. (deposition date: 2022-05-06, release date: 2022-09-07, Last modification date: 2023-10-18)
Primary citation	Manik, M.K.,Shi, Y.,Li, S.,Zaydman, M.A.,Damaraju, N.,Eastman, S.,Smith, T.G.,Gu, W.,Masic, V.,Mosaiab, T.,Weagley, J.S.,Hancock, S.J.,Vasquez, E.,Hartley-Tassell, L.,Kargios, N.,Maruta, N.,Lim, B.Y.J.,Burdett, H.,Landsberg, M.J.,Schembri, M.A.,Prokes, I.,Song, L.,Grant, M.,DiAntonio, A.,Nanson, J.D.,Guo, M.,Milbrandt, J.,Ve, T.,Kobe, B. Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling. Science, 377:eadc8969-eadc8969, 2022 Cited by PubMed: 36048923 DOI: 10.1126/science.adc8969 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.42 Å)

Structure validation