7UXK

Structure of CDK2 in complex with FP24322, a Helicon Polypeptide

Summary for 7UXK

Entry DOI	10.2210/pdb7uxk/pdb
Related	7UWI 7UWO
Descriptor	Cyclin-dependent kinase 2, FP24322, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	complex, stapled, transferase
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	35681.40
Authors	Li, K.,Agarwal, S.,Tokareva, O.,Thomson, T.,Wahl, S.,Verdine, G.,McGee, J. (deposition date: 2022-05-05, release date: 2022-12-28, Last modification date: 2023-10-25)
Primary citation	Li, K.,Tokareva, O.S.,Thomson, T.M.,Wahl, S.C.T.,Travaline, T.L.,Ramirez, J.D.,Choudary, S.K.,Agarwal, S.,Walkup 4th, W.G.,Olsen, T.J.,Brennan, M.J.,Verdine, G.L.,McGee, J.H. De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA, 119:e2210435119-e2210435119, 2022 Cited by PubMed: 36534810 DOI: 10.1073/pnas.2210435119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.63 Å)

Structure validation