7UVH
Pfs230 domain 1 bound by RUPA-32 Fab
Summary for 7UVH
Entry DOI | 10.2210/pdb7uvh/pdb |
Descriptor | RUPA-32 Fab Heavy Chain, RUPA-32 Fab Light Chain, Gametocyte surface protein P230, ... (8 entities in total) |
Functional Keywords | antibody-fragment, malaria transmission, cell invasion, cell invasion-immune system complex, cell invasion/immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 140816.32 |
Authors | Ivanochko, D.,Newton, J.,Julien, J.P. (deposition date: 2022-05-02, release date: 2023-02-15, Last modification date: 2023-10-25) |
Primary citation | Ivanochko, D.,Fabra-Garcia, A.,Teelen, K.,van de Vegte-Bolmer, M.,van Gemert, G.J.,Newton, J.,Semesi, A.,de Bruijni, M.,Bolscher, J.,Ramjith, J.,Szabat, M.,Vogt, S.,Kraft, L.,Duncan, S.,Lee, S.M.,Kamya, M.R.,Feeney, M.E.,Jagannathan, P.,Greenhouse, B.,Sauerwein, R.W.,Richter King, C.,MacGill, R.S.,Bousema, T.,Jore, M.M.,Julien, J.P. Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230. Immunity, 56:420-432.e7, 2023 Cited by PubMed: 36792575DOI: 10.1016/j.immuni.2023.01.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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