7UQW

PCC6803 Cyanophycinase S132DAP covalently bound to cyanophycin dimer

Summary for 7UQW

• Entry DOI: 10.2210/pdb7uqw/pdb
• Descriptor: Cyanophycinase, (2~{S})-4-[[(2~{S})-5-[[azanyl($l^{4}-azanylidene)methyl]amino]-1-$l^{1}-oxidanyl-1-oxidanylidene-pentan-2-yl]amino]-2-$l^{2}-azanyl-4-oxidanylidene-butanoic acid, SULFATE ION, ... (5 entities in total)
• Functional Keywords: cyanophycinase, cphb, cyanophycin, hydrolase
• Biological source: Synechocystis sp. PCC 6803
• Total number of polymer chains: 3
• Total formula weight: 92499.27

Authors

Sharon, I.,Schmeing, T.M. (deposition date: 2022-04-20, release date: 2022-08-10, Last modification date: 2023-10-18)

Primary citation

Sharon, I.,Grogg, M.,Hilvert, D.,Schmeing, T.M.
The structure of cyanophycinase in complex with a cyanophycin degradation intermediate.
Biochim Biophys Acta Gen Subj, 1866:130217-130217, 2022

PubMed Abstract: Cyanophycinases are serine protease family enzymes which are required for the metabolism of cyanophycin, the natural polymer multi-L-arginyl-poly(L-aspartic acid). Cyanophycinases degrade cyanophycin to β-Asp-Arg dipeptides, which enables use of this important store of fixed nitrogen.

PubMed: 35905922
DOI: 10.1016/j.bbagen.2022.130217

Experimental method

X-RAY DIFFRACTION (1.5 Å)