7UE5

PANK3 complex structure with compound PZ-3741

7UE5 の概要

• エントリーDOI: 10.2210/pdb7ue5/pdb
• 分子名称: Pantothenate kinase 3, 6-[4-({4-[(2R)-1,1,1-trifluoropropan-2-yl]phenyl}acetyl)piperazin-1-yl]pyridazine-3-carbonitrile, 6-[4-({4-[(2S)-1,1,1-trifluoropropan-2-yl]phenyl}acetyl)piperazin-1-yl]pyridazine-3-carbonitrile, ... (6 entities in total)
• 機能のキーワード: pank, substrate, complex, transferase, pantothenate kinase, inhibitor, activator
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43463.05

構造登録者

White, S.W.,Yun, M.,Lee, R.E. (登録日: 2022-03-21, 公開日: 2023-03-29, 最終更新日: 2023-10-25)

• 主引用文献: Tangallapally, R.,Edwards, A.,Subramanian, C.,Sharma, L.K.,Yun, M.,White, S.W.,Jackowski, S.,Rock, C.O.,Lee, R.E.; Discovery of hPANK Activators with Improved Pharmacological Properties; To Be Published,

実験手法

X-RAY DIFFRACTION (1.63 Å)