7UBI
Solution NMR structure of 8-residue Rosetta-designed cyclic peptide D8.21 in CDCl3 with cis/trans switching (TT conformation, 47%)
Summary for 7UBI
Entry DOI | 10.2210/pdb7ubi/pdb |
Related | 8CWA |
NMR Information | BMRB: 31003 |
Descriptor | Cyclic peptide D8.21 DVA-MLE-DPR-LEU-DVA-MLE-DPR-LEU (1 entity in total) |
Functional Keywords | cyclic peptide, non natural amino acids, cis/trans, switch peptides, de novo design, membrane permeability, de novo protein |
Biological source | synthetic construct |
Total number of polymer chains | 1 |
Total formula weight | 891.19 |
Authors | Ramelot, T.A.,Tejero, R.,Montelione, G.T. (deposition date: 2022-03-14, release date: 2022-09-14, Last modification date: 2022-09-28) |
Primary citation | Bhardwaj, G.,O'Connor, J.,Rettie, S.,Huang, Y.H.,Ramelot, T.A.,Mulligan, V.K.,Alpkilic, G.G.,Palmer, J.,Bera, A.K.,Bick, M.J.,Di Piazza, M.,Li, X.,Hosseinzadeh, P.,Craven, T.W.,Tejero, R.,Lauko, A.,Choi, R.,Glynn, C.,Dong, L.,Griffin, R.,van Voorhis, W.C.,Rodriguez, J.,Stewart, L.,Montelione, G.T.,Craik, D.,Baker, D. Accurate de novo design of membrane-traversing macrocycles. Cell, 185:3520-3532.e26, 2022 Cited by PubMed: 36041435DOI: 10.1016/j.cell.2022.07.019 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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