7UAH
Macrocyclic plasmin inhibitor
Summary for 7UAH
Entry DOI | 10.2210/pdb7uah/pdb |
Descriptor | Plasminogen, (6S,9R,19S,22R)-N-{[4-(aminomethyl)phenyl]methyl}-22-[(3-chlorobenzene-1-sulfonyl)amino]-3,12,21-trioxo-2,6,9,13,20-pentaazatetracyclo[22.2.2.2~6,9~.2~14,17~]dotriaconta-1(26),14,16,24,27,29-hexaene-19-carboxamide, SULFATE ION, ... (5 entities in total) |
Functional Keywords | protease, inhibitor, complex, blood clotting |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 56675.93 |
Authors | Guojie, W. (deposition date: 2022-03-12, release date: 2023-03-15, Last modification date: 2023-10-25) |
Primary citation | Wiedemeyer, S.J.A.,Wu, G.,Pham, T.L.P.,Lang-Henkel, H.,Perez Urzua, B.,Whisstock, J.C.,Law, R.H.P.,Steinmetzer, T. Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors. Chemmedchem, 18:e202200632-e202200632, 2023 Cited by PubMed: 36710259DOI: 10.1002/cmdc.202200632 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
Download full validation report